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Mouse element [ mm765 ]


Position: chr10:30,992,459-30,993,481 (UCSC browser)
Source: Lawrence Berkeley National Laboratory

Flanking genes: Hey2 - Hddc2

Timepoints:
e11.5

Published in: Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. He A, Gu F, Hu Y, Ma Q, Yi Ye L, Akiyama JA, Visel A, Pennacchio LA, Pu WT. Nat Commun. 2014 Sep 24;5:4907. doi: 10.1038/ncomms5907. PMID: 25249388

This sequence did not show observable enhancer activities at E11.5
We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution.


Fasta sequence
atgaTGTCCCATGGTTCCATACACaatgagtaacagaccatttctgggttctcacttcca
cttttaatgaacactgacactaactgacagtaacatgtagctgctcttggttatactcat
ccttcattgaggtcataggggtgtcagtaatgtaatttattaccaagtaaggcatgttcc
aagactctcatggtgaggaccacttttgcaagtgcaaacgccctgcaaggcaggcttctc
ttgataaggtaacatgctccatagttcctgaccttggcttaatgacgcttcaaagtcaca
gtgattccacttgactgctgcaaagatttcccaaacacactaccatctgctgggagggac
agagagccagtgtctgaagaactactgcttcaaactaagaagccacattgagaccccctg
agagatcagaacagcattgtgttctgatattcagtatctgccataaattctttcttcagc
ttggcagtcatacctcaggattaaggaaaaaaaaaaacactaaaaaaggccgtatcaaag
atctctatttaggagaatggcaggtacccaagcctttgtgtgccctgcagtgaggtcacc
caggcagcctgctttaagacacaactctgcactccctgtgaactctaccaaattagcttt
acatgatgaagccatcttgcttctctagaggatcaaagtagctggactgagtcccagtgc
tctgtagataaccagtcacaggatacatttgcaccctgctgtatatcatgctgtggattc
ctctgtatttctctttttatttccatagagggaacttgggttcacatatttccctgtatt
atctgagctaatctgtacactccactccccttagagtgcctctggaactgtgtaacattg
tttttctcatgtatggagctactgttcccaacggagtccttttatccttcctataataac
ctttgtaataggaacagcacctccttgtaacacttaaaatgcTTTCCTCACAAGAACAAG
GGA
Primer
(+)caccTGTCCCATGGTTCCATACAC
(+)TCCCTTGTTCTTGTGAGGAAA


For commercial licensing of the VISTA Enhancer Browser and its associated data please contact Virginia de la Puente (vtdelapuente@lbl.gov) at the Berkeley Lab's Innovation and Partnerships Office.