Mouse element [ mm759 ]Position: chr8:80,246,883-80,247,838 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: Ednra(intragenic) Timepoints: e11.5 Published in: Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. He A, Gu F, Hu Y, Ma Q, Yi Ye L, Akiyama JA, Visel A, Pennacchio LA, Pu WT. Nat Commun. 2014 Sep 24;5:4907. doi: 10.1038/ncomms5907. PMID: 25249388 This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence aACCTCTTTCGAATCCATGCTTtcccaaggacggatctgtagctcattttggtatatttc agtcaagctttgccgggcatctggctctagagccagagctctagagaagcaactcacatt cagaccagaaggacatgtctatggagtcagcatctttccttttgtgggtctagagtttgg tggcatacaaaagctgaccccttagtgctttccctagttaatacatcagattctcagagc aaatgtccacttgccattagtaatttggaaaatccaacggcgcccaaaccgcacacatac ttagggcaggtaatttacatggtatggttgccaaggtgtttcatagccaatctttaaaaa cagatgagttgatggctgtgtgggaatcagaaacaactacaagaagaaaaaaaaaattaa accaagaactttttttttttcaagttctctgtggttttgttctctggagaagacaaatta tccactctccttggacacatcctctgactttcatatgctttcgccccaggtctgctgggg tgaggccactaagggtggtgtaatcagaggtggcttatctacaaacagttccagggttct gcacatgaaagacaagaagtgccctttaaaggacaggacagcactgagcaaatcgcccag acctccaccagcaggcagatttccaaccccagctgccatcgtggtgtgaggagggctcca cagaggttggttcttcacagtaagtgtccttggcactcagggtgcaggataggaagagac caacttcaccaggaggctttggagcaagcgccctgggccttgatgcgcctgaaagcttgt gtggagaaaaagatcctcccactcccggctcccctttcctaaaaatccgagacaaagctc aatggtcttgtccggtgtccacccccactccccccaGTGTTCGTCTCCCAGGAAAGPrimer
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