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Mouse element [ mm759 ]


Position: chr8:80,246,883-80,247,838 (UCSC browser)
Source: Lawrence Berkeley National Laboratory

Flanking genes: Ednra(intragenic)

Timepoints:
e11.5

Published in: Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. He A, Gu F, Hu Y, Ma Q, Yi Ye L, Akiyama JA, Visel A, Pennacchio LA, Pu WT. Nat Commun. 2014 Sep 24;5:4907. doi: 10.1038/ncomms5907. PMID: 25249388

This sequence did not show observable enhancer activities at E11.5
We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution.


Fasta sequence
aACCTCTTTCGAATCCATGCTTtcccaaggacggatctgtagctcattttggtatatttc
agtcaagctttgccgggcatctggctctagagccagagctctagagaagcaactcacatt
cagaccagaaggacatgtctatggagtcagcatctttccttttgtgggtctagagtttgg
tggcatacaaaagctgaccccttagtgctttccctagttaatacatcagattctcagagc
aaatgtccacttgccattagtaatttggaaaatccaacggcgcccaaaccgcacacatac
ttagggcaggtaatttacatggtatggttgccaaggtgtttcatagccaatctttaaaaa
cagatgagttgatggctgtgtgggaatcagaaacaactacaagaagaaaaaaaaaattaa
accaagaactttttttttttcaagttctctgtggttttgttctctggagaagacaaatta
tccactctccttggacacatcctctgactttcatatgctttcgccccaggtctgctgggg
tgaggccactaagggtggtgtaatcagaggtggcttatctacaaacagttccagggttct
gcacatgaaagacaagaagtgccctttaaaggacaggacagcactgagcaaatcgcccag
acctccaccagcaggcagatttccaaccccagctgccatcgtggtgtgaggagggctcca
cagaggttggttcttcacagtaagtgtccttggcactcagggtgcaggataggaagagac
caacttcaccaggaggctttggagcaagcgccctgggccttgatgcgcctgaaagcttgt
gtggagaaaaagatcctcccactcccggctcccctttcctaaaaatccgagacaaagctc
aatggtcttgtccggtgtccacccccactccccccaGTGTTCGTCTCCCAGGAAAG
Primer
(+)caCCTCTTTCGAATCCATGCTT
(+)CTTTCCTGGGAGACGAACAC


For commercial licensing of the VISTA Enhancer Browser and its associated data please contact Virginia de la Puente (vtdelapuente@lbl.gov) at the Berkeley Lab's Innovation and Partnerships Office.