Human element [ hs2320 ]Position: chr6:136,644,543-136,647,656 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: BCLAF1 - MAP7 Timepoints: e11.5 Published in: Parker SC, Stitzel ML, Taylor DL, Orozco JM, Erdos MR, Akiyama JA, van Bueren KL, Chines PS, Narisu N; NISC Comparative Sequencing Program, Black BL, Visel A, Pennacchio LA, Collins FS. 2014. Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants. Proc Natl Acad Sci U S A, 110(44). This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence TTTGTTTGTGTCATCTCTGATttctttgagcagtggtttatagttctccttgcagagatc tttcacctcccttgttagctgtattcctaggtatttttttttttgtgtgtgtgtgtgtca gttgtgaatgggagttcatttgtgatttggctctcagcttgactgttgttggtatatagg aatgctagcgatttttgcacattgattttgtgtcatgagactgctgaggttgcttattat acactgcggttgtgaggttaaattcctcctttgggaaacttcagtttttgctcttcaggc cttcagctgattggatgaggctcacccacatgaaggagggtcatttgctttacttagtct tctgatttaaatgttaattatatcacacaatacctccacagcaacattcaggctatgctt gagcaaacaacagggcaccatagcctagccaagttgacagtccagtgtaaagtccatcct tgatacttctggtagccctggtcaagcattttcctctttggtctcagtctgcccatgtgt aagagaggtggctatattaggaaggtttccagggccttccaggtgaaatgttcctgcttc atccaggagacctgatgaccccaggtacaggcagtagaaagtactttgtgggctcctgta cagacctcttccccaggggttgagcacccccatctctgtttctgtcagtgtctccctgat tcttattctcctctttgcattctgccatgcacatagtccaaggggccaccagcccagccc caaattggcatgttatgacaattccatcacccattacggattagcatagctgtgtccctt aattcagattccagggagagacagtatttggttgctggccagccagctggatggctggag ctgtgtcaggtaccaactccaggtttaaccagctctggttgggagcagaatcctttggcc agctgccagctcagcaggtgctatgggaacagattcctggagaaaagccccgtggggagg gaggcggccaggagataggggctgcccgggcagttcaaattgactgatgcgtccattaca gttcctttacgcttaatgatctgctgccttgctgttgtcactgttgatttgtttggtctg tggagactgtgtggaccacatggcattaaaccccacatcaagggcactcatgctgatcat gacagccatggaaaggagtagagaggaaaatattttgagggcaaacagatcaagaatgag aaagccgcttttgccctcactaatgaccctaaaatttactcaatgatccagaaaccctaa aagtaaagccattagtcacaatgttgtcagagtaaaaaggaaagaaagaataagccgtgt gttatcattttagaatccattccacacaagtgcccatttcaaacgcctgaatgcctgaac catgcaggttgatttaattatcgtttgccctgcatgctatggagtcagccacatgccctg cacaccccagcatcaggggatggcctgtgtcaagctgagggctcgtgcatttcctttgtg cgcaggggctggggctttcttgcctgcccagctgagctgtcctcctgtcagctttgaggg cagcggtgtccagtctccgacggtgatgtagacaggacctccgcatcacttctaggacat ctctaggtggagagtgagaaagagagggagaatgctcaaacaggttggggggctcaagaa cacctcccgtgagtggggggcagcccacttgggggtgggagcactccctgatttcctggt aagttgccgcataatatgtaatcattagattatttgtttacttgtttctctcccctgata gactaaattcacagagggcaaagctcttgtcttgactttgcaataataatagttttcatt ggttgattgcctgctattggccatgttctatgttgaattctttacatatattagctctaa tctgcatggtagattatcgctctttgacagacagggaaatggaggctccaagaggttaag tacattgtccaaagttagacagctgtatgggacacagttggaatttaaactcatggactt ttcatctttccaagagcctcttacatacgtgatgtctgcaccatactgagtattaaatac atacctgtggaatgaatgaagatatacgcagctgcttctcttcctcttctctatggctcc tctatggcctgttgaactttgggagacaaggttggctgttggcaaaatttgaaaatctgc cctccctttctttgtgtctttcctattttgcaagctaccattccggacctagaagcaaca caatgtagtggaaagaacactcaatttggatttcaacagagctggcttggaaccctggct ccaccgaaagctctctggagttatttaacctctttgaacctcaggttccctgtctatata atgagaataacagcacccatggcagaaacatggcgaggatttggtggcacaaggatgtaa gtggcacctgggcactgggctcagaggtggtattcaggaagtggaagttcccccattttc ccccagccaccttcatgcctgatctctgccccactcttgggctttagagacacgtgctgg ggtcttggttcctggaaagataaagtgctacaaaaattaaattctagaaaatcctacaga aaactagaaaactcggttctctgaactttagtcattaaaagtgtcacacgcaagggatga aagattttaatttgattcaattcagttctgttctgcagacactggcgccacagcccctgc agtaggcaatgagctggcctgaggacacagaactcctgtctcaaggtgttcacactcagc tctgggggaaagacagctatgaagcaaatagtttgaaatgtagaacccttgggtacaaca gagaactgtgtagtaggtcccaaagcggcacaatgggagcaggggcacagaagggcagag agccaggggaggcctctcagaggatgaaatgaataaggtgagtattaagggatgaatagg tgtttacctgctaggagaggaggtaggaaagtcacaggaaccagcctgtgaaagagatGG AGAGGCCACACTGTPrimer
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