Mouse element [ mm2211 ]Position: chr9:63,849,928-63,854,559 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: Smad6(intragenic) Timepoints: e11.5 This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence GCCTGTGCTGTGAAGCTTTCcctaacacccacaatctcttcctcttcgatgtagctttgt ctcaagctgtgtatcgaggcaatgaagagagggtccgctaagacagtgtacgccataaag gccagccttgaaacccatccacctcctacggtccgagagctggaaccagcatccagaggc acattggcaccatggagctagagaccctgacccagtgggctccttgcagcaccacaaact gaggtgctggaggcaagggtcttgcttgcttggagccacccagcagcaaagagcaaagct aagcttggaacccatcctggcaaactgccttatcccatgatgctccagggcatacccctg aaggtacccctgtgcccgtcacccccagcaaccagcctgggaaaatggagcgtctgtcag gagcataaagaagagaaaatgaaaatttaaaaaaaaaaaaaaaagagcccaaggaagggg cttgccactaacactgtccatgggaggacagcaccggctgttcccccactatcccaagat gcctctcttatccagggcacccccatgatcaagtatgaggccacccgcccgtagtctcac tccaagacctaagaaaatcatcttttcagctcgcgcttcctccaggccctgctggccacc aggtgtgtctgctactggaacactctgagctggctggccctgaacccctgcctcccccgg ggagacggttccactgggtgaggtgcatgccacaaagctgacaactgagttggatcgcta ggtcccacatgagtgggaggagaaaagcaactcccatgaagccgtgctgtgacactcaag ctcacacgcgtgtgcacatatgaacagcccacagtgcacatataaatgcatcacatattc acgtataaagagacaaacaatggcagacacttccagccatccgttaaaaccccacctggg taccccctcttctgagactcctggcggcctctcaacaggaggctcccaattgcctcctac cacagcacctgacgtgggcgcctggaggggaattgatacaggtcttatctccaggctggg gacctttaacagctgcaccctcacacaggactaaaccttcctggccagagcgtattacta ttgccccccattccacaagtagaaaaactgaggggcagattggctaagcagctgcctccc ccaccccaactaatcaggaggcagagcggggacttgaacagagagctaactgtgatgaag cctctgcctgccacttacctcggctgcaagagtagatgtgtgctggctgaagctgacaga cccttagggacacagagacacagagagcctgggctgaacaagccctgtgaccccggcagt caaagagaggcagtgacactgtcacatctgtatgcacttgaagatgtgggcaaagagcac tcagctgagagccaagggccatgggacagagagcaggtgaacaaacaacacagggctact tcttgacgactaactccagctactaactagtgcttgctgtgtgcctcacagccagcctca gtttctctgagcctgtctccaaactgttagcttgaatgtaagcccggataggaaggcctg ggagggaccctaaggagcttcagattaggcagacactgatccagcttagccccaaccccc acagcagtactgcctgctcctgaggagggtatgccccagtgacccagctggggctgagag gctagccaacacagtcaaggccaacagaagggcctagtagtctccactacagcagcttat atggcatacggacattgctggattaaataaacacctggccaattatctgtgaggctcctg attagttaccaaatggtaattgtggggtgtacagatgccagccgggtgccccagcatggg attgggcaggcctatgtgttcagcagcctgccaccttgagttctcatgggataactatag ttcttccttctctcacccatccagggcactctcttcttctaggttggagtagaggatgct ggaagaatcttgcccatcccaccagctctcctcaaaccaccagttcccactaccccctca cgctgcacttccatgactgacagcatagtctgccttccaaaagagtacaacccacagcca ctcactcccaccagagtgagtttcttcagctgatcatgcttaatcctcaacatgctgatg tcaaggaagcaggagagaaatgtcagggctgttaagacgccacccaaaaggacaaggggt ccttagctagccaggggacagtaccccagacccaaatgaaacaagaaaaccataacccca gaggttcgagaacaccctcaaaagagacctcaaggctagtgattttacccaaatcccact gaagacactggaagtgaggatctatgggagctggttgatggttcacatcttgtctcccac ttgagtgaccttggtggagtcacctgtaccctttgaccttcagtttccttcgtggatcac aggacctgactgagggcccatgctgagagtggatgcctacagggactttggatagccagg agacaggaccccagtcgtaaatgaagtgacaacaccatagcaccagagttccaagtgcat cccccaaagagacctcattctgtccaattaaaacaggagcccccattccctgcagatcct cacgtgtccttatctgcctgggcctgtgcctgatccctaaatcctgccatcctcctatgt ggccttagtcacaggatgggagaacagagaaacaaaaaagtttggccaggctgtgattgt catcgtgtgcaggatagtctagatgtgagaatgaccaggtcgtcaagggcaccaatccat caggacacagaacagagggatagcacagtcactgttcggtgggtccctgtgttctccagg agagttcctccctggttgcacagagaagcacggtgtcctgtgttcctctcaccccagccc tggcactgaagttactccacccaagcctccatgggtcgtctgggaaccacagctgatcac tcagcagcgagagggagtagggcagaccagacagtctgatggggccttacagagactgtt ccagacgggggacagtgggaagaatggcagactgtctccctagatggccagtcgaggaga tgaagaacagttggtaatgatcttagagtgggggtcgagagacaccagcatcatcgccag cacggcaaccaccctattggtccctgaccatccaatgtcttggcctgacccactctgctc ctggcctttccaattctgaatccctcagtgctctcctgctcaccactcaaccccacagga tgaggaagtcatgactctcctatccaccaaggcctgtcatccatcccctgggactttccc ctacctgccaaggactccctttcctgagtcttccctctagccaataccaacacagcccaa agctcaggggaacacaaaaactgttccaattgcttacgcgggccatctagatcccaactc actccctcctcccacatgggaaaccccaaactttcttcccttatcttttagcctctcaga atgccaaccactagacacttttctttttctttttctttttccttttttcccatttgtttt caaggtatctctgtgtagccttggctgacctggattttactctatagaccaggctggcct caaattcataaagatctgcctgcctctgactcccaagtgctgagattaaggggtgagcca ccaccaccaccatcagccagcattctgcctggttcttcaacatagtttttggtgtttgtt tgtttgtttttgtcatttttttgtgactggtctctctctgtatctccagaaggctggaac tatagaacaggctggtctgtatcacagatgtttgtctgcctctgtgctcttaaaggccac cgcacgcaactacctgggcagatctttaagggagggaaaatataccaaataagaggagag agtaaagtggcctgaggaggggaccagggaccagagagcagacaggagctggagacggga gatctgtgccacatgagccacaagctcactgtagggtctcaccttcggcctccatctctt agaacagccatcttcctgtggtctcttcccaggacctcgggaagaccaggaaatgggcag ggaagggctctagattagggaaatggataagtgtctgggagcagccagtgctgtcacctt agaatcacaggagcacaagaagtgacaggcagaattctgggaatatagtcaccagggtgc actgaactgttacagaacaggggagggcagcacagtagttggaaggagctgaggttcctg tggccacaaagactgcgatgtggccctgagggatgcaaggagtcactacgcttataggtt gacagcccagctgccttgacgtaatgtaaggtgctggggtggagcctggctcaccctggc cactcagcctcactcttctgctcttttgtcttgaatgtagagtcagaaaaagatgcagag gcccagctagctatccccaactccaggccataagccgggctgccacacagtaCACTCTAC CGACCATGCTCCPrimer
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