Mouse element [ mm2202 ]Position: chr9:63,719,716-63,725,483 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: Smad3 - Smad6 Timepoints: e11.5 This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence CCACGTTATGAAACTGGCTCtggaatggttttttttttgtttgtttgcttgttttggttt tttgcctttctcaactgtgggatataccatacaaatatagtcagtcctttatttctgtat ttccatatccactcatttaatcaggaatagaccaaaaataattatgtatacatgcgcata agtaaaagtaaaatcaatagttgatacaatattttttttagatacaatatttttaattct tccaatttgtttcttctggctagatgtggtaccccacgcctgaaatcccagtgcttgaag gctgaggtagaaagaccatgatcttagaccatgatctaagtcgatttaggccagctagta tgactccatatcaaaacaacaacagaacattactcttccaaacatcgaaaagctatattc tctggttcttctcctcggatagttgacctagaaattacaactaactcatgtattctgggt tagtgagcagctgtcaataaatatctttactttcttcctgaatggtgtttgaagacctaa aacatttctgatccatttgattcctgatttatgtttggcattttttaattccaaagtctg tcattccctttaattccacatgtcatgactagtgtagcttaaaggatattttcttagtct tccatccaggcattgggtgttcttcaagattcctatactttctcctctgcctgagttcag gccccttccctccatccagcagttggttttgcctctactaatgtacttagagtggcaatt tattctttagttccatctgaaatatttcattttttaaagatttatttatgtatgtatgta cactgttgctctcttcagagacaccagaagagggtataggttcccactacagatggttgt tagccaccatgtggtggctgggaattgaactcaggacctctagaagagcaatcagtgctc tcaaccactgagccatctctccagccccgaaatatttcatttttacaacagctttgaaaa atgcctacagagttctagattgacacttgttttttgcccaacatatgcacaaatattcta gtttctttttaaaaacaaatatttatttttacttctaattatatgtgtgtgtgtgtgtgt gtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcaggcacccttgggagaca gaagagggtttccgatcccttggagctggattacggtgatcttcagtcgtccacttgttg ctatgtgagccagcagctaacctaaccatgttttcttctgcatacattgccatctgtttg ttcccccactctggcaattttgaagatctttgactttagctttgtccagtttcacccttt taaatccacaaataaattaaatttatttaacttatgtaagactccctagctttatctgca agctagtttatgtctcttctcaggtctagacatgttagccatcactcactaaatgtttac ctccactcattttccttctcctggaattcttacttggcgtatgtttggacttctccattc ctctccaagatccctgactcttccttcatagtccatatctcctcttctctccttgatata tttattcagctcgtgggttctcccttcagttgtgtctaatctattttacacataaaaagt gagttttccccaatgatcttttttctttccatttctaaatatgtccttctttttagaatc tgtttttgttgtcaaaacaaaacaaaacaaaaacaaactaacaacaaaacagaaaacaaa acaaaacacttttctgtggatgggatttcacgccttaaatcagaacgctcaggaggcaac cacaggtggctctctgtgagtttgaggcccatgttctccaggaagggtggtctggttccc tctgtctcatcccttgctgcggtaacctcttggtccattgttctcctcagctccagtctc tactcttctctgagatcagcttgcctggcctcggattgccagctccagctagatctcttc tgctgcgtgcatgactctgagccctcagtaccttgagattcccatgaagctaccatgtcc caagcatcgagacatcccttgcctcttctctggtaccagaggccatagtaaaggatgtat ctctccctaggactatggggcccttggagcctggctgaagtctgcttctccctggttttg cagatctcagctttgagcagagtggctgtgagtgtctgcttctcagtccatgtgtaccct ggtgtcagtcaggcacagaagggtcctgtggacatagcaggcaggagctatcaccataaa cgatcagaatgaagcatgggagtgtggtgacacagactttccatcccagctgctgaggag gtggcatctggagagtctcaggttcaaagagcatgagttcaaggtcagcctgggcaaagc agtgggacgctgttcccaaataaaaagtaaaaagaggtcttaaaatgtgtcttagtgata aagcgcctaactgggtagcatgcatcagaacttcaatccccatcacagaggggggagggg gggagggaggaggggagggagggaggggggcagggaaggagggagggagggaggggggca gggaaggagggagggagggaggaagatcacataaggtaaagataattttcaaactagaaa ttgtaataataaattcaaaagttaaaaatagttgtgagccaggcgtggtggtgcacgcct ttaatcccagcactggggaggcagaggcaggtggatttctgagttcgaggccagcctggt ctacagagtgagttccaggacagccagggatacacagagaaaccctgtctcgaaaaaaaa caaaaacaaaaaaattaaaattaaaaaaaatagttatgaaaaataaaatcaactgaacct gaacaatgctagaactacattgattcttcaagacatcccttgtctcttctctggtatcag aggccatagaaaaagatgtcttaaagctaaattgatgacattaatatgtgagagtattca ttttaaagcaactcaaagaattatttcccgttaaaattttaagatggccaggaacatgcc tgtatcccagcacgtgagaggcagaggcaggcagagctctgtgagtccaagttctacctc acaggttctagaccagccagagttacatggtgagaccctgcctcaaaaaaaaaaaaaaaa aaaaaaaaagaaagaaaagaaaagaaaagaaaaaagaaaaaaagaaattaagaagtctga ttaaagtggtctaaacaggaactgaggtaaggagttgtgaagtggatgataaaacctaca agctggcgctggggagatggctcagggggcaggcacactccctcttgttgcagaggaccc gggttcatgcctagcatccacgctgggcagctcccaaccaccataactccagctccagga gctctgatgccctcttctggcttccacaggcaactgcactcgcggagcatatacatccaa atacacagaattttaaaactaagataaatattttttaaaaaacaacaaacaatgctcaca tggggagtcaaaaggggtgcaggtgaccctctgctgaactctcagtccccacttgcacac actgatgcatgcacacagatatacaaatataaataaaataacatgaacagcagaaagcaa ggtgtgtcacaggtctttttatgtcaatactaaccttaggctagggcacaccaggcacta gtggcttttcatccttacactagctgtgtgaggtaaattctatcattgtccccattttac agctttggagactgaggtcatgggggacttgagacttagagtgggtcttacacacttgcc tcttctctggggcctcttctcacttggggcacacagtggctttgacattgcgcattggtg caatcttctttgtggacccagacccgtgcgctcacgtcagactttttttccctaacccct ctgcttcaggacacagcgtttctcctgctcccatgtcccattggcttcttagttttaagt cccgtgcctctggggcccagagatgccttaagagagtcttgggaagcctgatatgaagat ggggtctcctgaggactgtgaccccatgagcctgtggcaccgccctatttggagaaccag gtgccaacgtcatcgggactgtgaaaagggccatccccctgcagctccaccttggggggc tacccctagcccagaagctgaaccatacacacagcacacagcatagcacaggccctgcgg gtgtaccgggtgcggaagtcacttgagcgacttgcccaggcagcctccccgctcaatgtc agccgcaggctcttagtacatccatcatctagtccttaagacatattaaaatggatttaa aaaggcatttcacattttctctccttaacatccacattattaccacgcatcggcttttgt tttaattaaaatcggttttgaaatcctccatgaaacttcagtgggattgttaaaggcggc aatttccttatcggcaccgagtccccacaacatactgtaatagttattttgcaacaaagc gcaagtcttattaatttagctcaatcaaatcagcaccgcgttaatttacggggctgtaaa aatctgccagtgctgctctagatcagagaacttaggggcaggcgggacaccaagtgcgat gtttattttgtacaatggtccctaactgcatctgcgtgatttaagagctttccgagctcg gataatatcacatgcatacagcattgtgtgtctacgcctcattactccctacagagaccc aaaatcatttggcattcaactcctgcctaaaatatttccttctacatacaaatatttttc ctgctttaaatgacttccctatgttaatttttcccccctttttggcttggcactgtgaaa caaggtactttcccgtgtgggcttctattttggtcccgtactgaatcttactggtagttg ctgagccagtggtgggctctccccgcccccgcccccgcccccacgcctcttcttttcctc caaaccgggagctcatgaagcttccgtgaatggttgctggatttttctgcttcctggttt tcttttaccagtgtcttcttcaggagctacgagcatttacttctctggttctcctcgcag taacaaagctgcagaagagggtgctgtgctgagtcctgggtgcagggtgcagggttcagg gtgccgggtgaaggctgagtcccgggtgcaggcatggagtgcaaggatgatgtgggttgg aaagccgtgactggtgggaatgaagaggtggagcatcagagagaatgtgtgacttgcctg aggtcacactgaggcagaaacagcagtgggtgcagatgacctcgcctctgatccaatctg tttgttttgaggcagggtctgaagcagacaagttaatctgtagttgaggatacctttgaa cttctgatcctcctgcctctacctccaaaggctgggatggccggtgctcgcccctatgcc cagtttatgtagtactggagattagactcagggctttatgcgtgttaggcaagcactcta ccggctcaacccggatcttctgagcccttcagatggtggaagactgtttgattagttgtg gtggataccagagcttgctggggcagagcccttgcttttcagtgtcagCTATGGTGGGTG TGACAGTCPrimer
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