Mouse element [ mm2180 ]Position: chr9:63,694,087-63,698,917 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: Smad3 - Smad6 Timepoints: This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence CCCCCAAACTCAAAAATAAATAAGTTAAGAATAAAAAATAgggctggtgagatggctcag tgggttagagcacccgactgctcttccgaaggtccagagttcaaatcccagcaaccacat ggtggctcacaaccatccgtaacaagatctgactccctcttctggtgtgtctgaagacag ctacagtgtacttacatataataaataaataaatcttaaaaaaaaaaaaaaaaagaataa aaaataattactaaagcctccctctgcacagtcatgttggcctttcctgagctgggcaga gttccctccactgtgatgtgcaaatttccacacagttcttccacttccacttagaagacc caatggcacagccctcctatttagaggggaaactgaggctcagatgtagtaatgccccca aggtcttggtcacacagaggtgtctagactcaacggggcatccagcacacgtgcctgtgc acacaccttgtgctggggcagcctgggcagaagcagggccagccttgtgctgaggctgtg aacagtattggggagtctccagcgggcactggggccaacccaggagagctgggacaaagg caggctcctgagagaacgtggacctaagctctccaaacgtgcttgacactggtagctggg gacaaggctggtctataggagacaaggctgacctataggggacggggctggcctataggg gacacggctgacctacagaacactggggcaccattctgctgggtcaccctgcccaagaag acaccagcccctgagacatgaagtcacacatcagagtcacaatggaaggaagccgtccta tcaccaccgtggctggatccaattcgatgtgatcttagagccagtgagagccaatgagca gaaggcagcttcgagagcgctgggctccttgttgcacagattctccaatcgagtggccat gtgactgaacgtaaagtcatgaaaaaatgaggtaacagtacgatgtttctgaacacacgg tgcccacaattgaagtataaaccaaaagtgtgcagaagttgaggtgtttctggaagcact cacccatgccatgtgctatgactttcctgaacccttggttctggtaacacactgtgtgtc ctctgcgtgatgtgtgctatcatgtcgaccccctaaaaccacatgtcaccatgtaagacc aacaaacagtgcccactgaacacctgggttcacatataaggctcctctgtggattttttt ttctttctgtatgtgaaaaaagttttgttcttgtagaaatgtgatttcaaacttttataa agacatacatattacttttatgtatatgtgtggtttgcatgcttgggtttatatgcacca catgtgtgtagaagcccacagagaccagaagatggcactggattctctggaactagaatc acagatggttgtgagtcacctgatgtgggtgctgtggattgaacctgggtcctctgcaag agctgcaaatgcccctaaccactgagccacccctccagctcccagaacataatgtttgaa caatggaaacacagatgttaatattctcctaccctcattccttagcacatcaatatcatg ttaagatatgtttggattacagcgtgagaacattgagtctcaacctgtgggttgcaaata tcagatctttacattacaattcctaacagtagcaaaattaaagttatgaagtagcaataa aataagtttatggttgggggtcaccataacacgaggaactgtgttaaagggtcacagcat taggaaggttgagaaccactgtgttacactgtttgattataaaaactgctgtttgaattg ttgcctttgggtcagagaatggctctgtgggtaatggctttgacaccagcccctgagaca tgaagtcacacatcagagtcacaatggaaggaagctgtcctatcaccaccgtggctggat ccgatgcgatgtgaccttagagccagtgagagccaatgagcagaaggcagcttcgagagc gctgggctccttgttgcacagattctccaatcgagtggccatgtgactgaacgtaaagtc atgaaaaatggggcaacagtacgatgtttctgaacacacggtgcccacaattgaagtata aaccaaaagtgtgcagaacttgaggtgtttctggaagcactcacccatgccatgtgctat gactttcctgaacccttggtggccacccttctgctactttgcactacatagttattgaag tgacatttcactcacctccaacgtttataaaatcaaaatatccatcggctctgaaagcat tgaagacgccatgttctacggtgtccggaggccagcaagagtccatcctttctgtaaatg caagcaaacacatccaccccattgccctaaacttcagttttaataaatgggaaggttatg tttgctaggaactcttttaaaataaacttctctgtaatttatgatcaataaatgttttaa ctaacatgcctctttcatatgctcagggtcacatacatttctcaagcaaaaaaaggattc tcaagaggaaaaggtttgagcagtattgacttagcatatgcttcatctatatgaactggc ttcattcgaagatctggactcacaagcacagagaggttcaggaatacgcctgaagccaca cagcatcccaactcaggtctcccttcctccctttacgctttagcttattcccaagtgtgc tccactgctgcccgttgctgtcctcaaaggcctagtagactaaacactagggaagctttt agcggagcagttatcctcccgctagtctatcagacgtcatcttaatccattttgtgaatc ggtgaccacgaggctaggcagacacaggtccttcgaacccttttatcttgaaccactgcc tcaggggtgtgttgagctgcacgtaggataactgcctctcccaggagaaggctggcgtgg tgactcagacatgcaggaacacaggcgccttctagcacctgctctgccacactgagcagg taacttccatggtcatgtttgcaaaaacagctgcagtccttacatcccaggcagaagaaa aggaaagggaagagcaaagtgactggaacccagaagccctggcagcatctcacaaagact agacttcagctgacctctcactgggcggaaatacgtcacatgactagccgcagcggacct tgggaggttgagtgttcgaaaatataccgtcctgggtgggagtggagctttctgagtaag gaagcaaagaatactggacaacgtagacatcctttcctaactcagggggtctgaagtgag gctcggagcttggagatgactcaggggtaagagagctggctgctcttctggacgaccagg aatgccattcccagcacccaagcggtgacacacagccatctgcgattccagttcaagggg atctttcgccctcttctggcgtctgtgtgtactgcatgcatgaggtgcacagacaagcaa gcaaaaacacacacactcacacactctcacacacactcacacatacattcacacactcac atacacactcacacactctctctctctcacacacacatatatgtataaaagtatatatat atatgtatgtattttaaaggtccatttatttttaataactatatcatcttccttttattt ctctaccaagtcaaagccccctcactcttcagggacacaaaggagcccgactcggctatg ctccaggttcctacagccacctcctccggacacagctcctctgtagtgaggaccacagat agccagctcctttgctgcgtcacctgttgctaggaagggaagggcataactcatttgcat atacatgttgccaccaggacaagactcagccccaaacccaattaactgcccaagagcaca gcgcagacagaagggtgtagaacccctcacttggtgataccaacatagccagtagaacac aaagggcatttttaactcagtccctgggcactgtggtggaggcagggctgaggacaggat gatccagtctaaacgtcactggtatatggggccagctgcctgtcccttccatcagcctta tgcctgacttcctccattcaacttcaaactgcggtagatgaggcaatatctctctatggt gagggaacaaacctctctcatggagccccaccctcttgatctaacctctttctcacactg tcacactgaaaggacagatttcaacacacaagagtgaggccaccaatccattaccattca cttctgtccaccccccagatctgtgtctcaatctagaagggagacacatgccatgtctac acctaccctcagctcaaccccaggatagggacaggctctgcatggcccagcttaggtcag aagcacctggtctaaccacgtgtgtcctccacagagagagaggtcggaccctgagtagga cagcaacaaaggccattcaacggacgccccacaatgacacgcctattccccttagggtgc tgtcctgtatcagacatgaccattccacctttctgtctttttggtgctggactgacccca ggatcttttttttttttttttttttttttttggttttttgaaacagggtttctctgtata gtcctggctgtcctggaactcactttgtagaccaggctggcctcaaacccagaaatccac ctgcctctgcctcccaagtgctgggattaaaggcgtgtgccaccaccacccggctGACCC CAGGATCCTGTGTGTGCCTAGCAGGGTCCCCPrimer
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