Mouse element [ mm2142 ]Position: chr9:63,876,446-63,881,152 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: Smad6 - 1700055C04Rik Timepoints: e11.5 This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence GCTTCCCACACGTTCTCTGAtaccccaggctttactgtgggtgccatatgcctttctgtt tgaaccccaagcctcccttccttgcaggaccctgacattggcaggcccctcttcctcaga acttgagataacttgccacacccctagcctagcaccctggggacactccagtaatgttgg gagaagggaggcagattggaatttctaacagagtcagccagcttgccctccagtctgcat aagacttatgtccatcagtcctcactctcagcctacgcacaccccacagatgcacttgca aaggagggctgtgtgctacttctgacatgtgcaaagtctcatccgtaactattattttat aagaaaagacaggctctgggctttttggtttcactgacagtgtaactctggctgtcctgg aactcaatctgtagaccagactgaccttgaactcagagatttgcctgcctctgcttccta agggctggaatcaaaggtgtgcaccaccatcacccagcgataaattgttaaaaatataaa agaaataagagagaaagcaggaaacctaagggtttgaccacagtggacattatgccacag gcccatccctgctgtacagagactgaagccatgtccctcaacgctaggcaaggtctctgc ctttgagcaacatagctagcccactacattattgttcacattcatttttatttttgtttc atttttgaaacagtgtttcatgtaatccaggctagctattaacttactgtgtagctgagg atggcttgaacttttgatagccctgtctctgctttctggggtgttttctaagactatagg catgtgccactacacccagctaaccttgactaaaaagcatgtgtttacagatacacaaac tggaaatatgcacaattaaaaccaggcattggtggtacctgcttgtcacggagacagggg gattaacacaactcccaggctatcctaggctaccatgtgagtccctgtctggggacaggc ctggtaaagaggaatggactcactcttcaacacagaaccatttggtggtctgttcaattg cttgttatttggtttggttgtactgtagtgttgttgtcttttgatataacagtctcacta tatagcacagattggtctcaaacttaccatcctcctgcctcagtctctcctgggattaca ggcagtatcctccaccactcccaactttgttatctttatctttttagatctatttaataa ttaattaattttggagggcttgtgtgccctggaacaagtgtggaggtcagaatgcaaatt gtaagagctggttctttctccagtgtggatcccagggaacaaactaaggatatcaagctt ggctgcaagtgcccttccccaaagccgtccaatagtaaatcgctaatacttgtgcttggt acaaggtctagatagtcctattcagtaccaaagccacatcctgctctctgtttcctgcac cctggcaggcagtcccaggtggacacctgtcagttccctccccaagctgaatccttagaa atagttaaatcaaaagctcaggaatgacaaatttgctgtctaaattattaacagtggttg cagaaaggaagaaaatcaacaaaagaattgtttattaaagaatcctaatctctgaaacag tccattgacctgcaaagcaggacatgactcaaatgacaaatgaaatgacaagaccaagca gagacagaggtaggagctgacgacagtggggcggtacatcctgtctcgccttgcttggga cttcctgtgtgtatgtcttcctttccagcctggccagggctggcttcatgcttttgtttg ctccagagcctggtgcacagaggccatcagaaacacaccctatcctcattccgtctggca caagtcaccttcagagaagggacagaagacagagtcacccacatcctccagagcctggtg ctggacacaaggcaacattatgacccctgcagaccctggacacctccatctttggacaca tactttcataaataattgaaaacatatttcacaaatgcattcacataagaaccatatcca ggctagacttgttggtctctatttatttttatcacgatgtaggcctagtgggcctggagg tagcctgataagtcctgttcctccagctctggcctctgggatagctgggattacagcccc gtgtgcctatgatgtaccaatcctactttataggatcctaaggatccaacccaggtcctt tggtactctaggctggcattctaaccatcgagttccatccttaacccttgtttcttttga atttaaacaaaactaaaacattctgtaaaggattgtggatggcaggcactgcagacacag tgcctaatgggtaagtagaccccggcttgagcctgtgtcctgagtatggcttgtatttac taaccagggatgcttcttaagaacagctgggttcagccaggcagtagtgatgcacgcctc tgattctagctgtgagttcgaggccagcctggtctacagagtaagttccaggatagccag ggttacacagagaaacctcatcttggaaaaacaaaacaaacaaacaaacaaacaaacaaa aaaccagacaaacaaaaagaacagctaggttctggggaaatttctttggttttgcatccc tgaagacccaagctgcagtctagtcccagaacttacctaccgggccacagccaggccacc actaaggctgcagtttattaaccctggtaatgtgccatctgctgctgattgagtagtctc cacaagagaagggatgatgctctagtgggtcaggcacacaagcgatcagaagtctgggtc ccttgggagaaagaggcaaaaggtggcggtggaggcacaggaagataacattcagctctc attccactaaggcactgggcctggcctatgttttccagtcacctgggtgttttgaaaacc attggctaaataacacacacacacacacacacacacacacacacacacaatatgcgcagt gtttcaggatatttgatcacactgtgaaccccaagattgtgtcaggtactgaataaaacc tgtttctagctgtggtatggctcagcccttagcacacacctttaatccctctatctggaa tacaggcatgcccttatatacaccttctattccaaacaactaaggtaaagttagtttata gaaggaagcacccatgtttgaaagtgacaaagtgatgaatcagagaaagatttgacaaaa taggatcttcccaactttcacaagaagagagaggaaaaggaagctacttaagtgagaagt gcagagagagggagaaagagagggggaagagagaggggaagagagagggggaaagggagc aagcagttttaccaggagagttttacagagataggatggggagagaacaagccagacact ggtaaagacagaatgagccagagaattcgaaggagccagaagattagaacaaattgctac agttagtttaaggccatacagagcaattcaggagaagctgagagaagccagattgaccca gtaggcctggagaagagtttgagccagaacagctcagttgaatcagccaggcagagatca gaaagaagggatgagcttattcagcagtaagtctgtctcagaggctaaaagcattctaga cccagattagattgtacggaggctggaagcatccatgattagtcctaggtccacagacag aggcagtacgcctctgaaatgacagtaaaggcaatgtctacaacccagcccaacctcatg agtactgagacttcaggtaggagccaccaggcctggcttgaggagtaccaggcaagctct cagcagctgccagaggcagaatggaactggaatatctgtctctcatggtctttccaccct cccttctgcagtgctccctgggccttaagtgtgggagtgttttgtagatatatctgttgg gggaatgggctccacaagtctgcattatgataggctgtggtcttctctaatggtctctgt ctgttgtaaagagaagtttccttgatgagggataaagactacacttatctgtgggtataa ggactaaagtttatagagcgttgttaggaattatgctgatttggtaaattaatagttgtg gattctcctgcaataactgacttcactagcactaagaagttagctaggtttccagtacca gacatggtttgcctcttgttgagggggccctaagtctaaagagttgttggtcactgccaa ggtattcgtgtcactactgcacccaccctcagggttatcatgccacactggtcactgatg cacataggcgtttgcctgcatgtttgtctgtgtatcacatgtatgtctggttccctcaaa gactagaagtgaatgtcagagtccctgagactagagtaacagacagttgtaaactaccat gtgggtgcagagatctgagcctgggttctctggaagagctgccactgttcttaaccacta atccatctctgtagctttctactccttgtattctttttcttaaagacagtctctcaggct ggggatgtagttcaattggtagagtgcctaccaggcatacacaaagccatgagttcaatt ctccagcACCAAAGAAACAGGGTGGCAPrimer
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