Mouse element [ mm2123 ]Position: chr9:63,622,669-63,627,542 (UCSC browser) Source: Lawrence Berkeley National Laboratory Flanking genes: Smad3 - Smad6 Timepoints: e11.5 This sequence did not show observable enhancer activities at E11.5 We define a negative enhancer at this developmental stage when at least 3 transgenics were obtained and yet no reproducible pattern of expression was observed. This does not mean that this sequence is not an enhancer at another time point or a weak enhancer at this time point but below the detectable range at our level of resolution. Fasta sequence CTGGTCTTGCCCAGGTTAGGccagggttacagtatgagcaggtttccccgtccctgggta atgcccttgcacataactcacacatgaggaacgaatgcggccatgtttgtgcagagttta tttagataagaaagcagcctcagcctcctgggaggggccaccgcagagggcaaggcacaa gttagttattaatcaccatctgcaggaaggcagagttcttaaggcacagagcagcagagc aggcacagtgctagagtcaaaggcctgtgtccaagtccccataaatgccaggtagggtgg tggccagcctgtcattccagcctcggaaggcagagaggagtcccagagcaaactagcaac agagtctacgcatatgggtgagctctgagtttgattgagagtccctgaatgaggtgcaag agcaatcatggatgactcccaacatcagggctccacaggcatggctgactccatgtgcct gaaagtgagggctaaaacatagccttaaagctcaaaactgagtctgctctggctagaagc aggtgtgggcctagatccagggcctacccacaccacagttggccacccacccacctcctt ctctaatcctactcctcagcaacccacaaggtgcctcctctaagctctgcttagaggtgc acccaagccagcctccatctgtggggtacacaccccaactatgttcttacaaggaggagt ttgtgccaatgttctgagaagctgtgactttaagggacactgggaacaacccagatgtca atgcatagcgtcagttgcagtggtgcgtgtacatggagcaactttgaatgtgaaagtgaa tgtgggagccaaggtgagcaactaatagacaataggtcacatgatttgaccatgtcatgc aaaggtcacatgatctgaccatgacatgcaaaggtcacatgatctgaccatgtcatgcaa aggtcacatgatctgaccatgacatgcaaaggtcacatgagtggaccatgacatgcaaag gtcacatgatctgaccatgtcatgcaaaggtcacatgagtggaccatgacatgcaaaggc aagctgaggggtatgggcgttgggtgaagtctacatagatgcagaacgattgcacatgtt ggacggcacagtgagtatgacgttggctgtgggaaacaacaaagcttctagaagaaatca caggagaatatctataacgttggggagggccacgttttcctaaggcaggcacaaaagagc acaaactgtaaaataatgtcagtaaagtggtcttcattagcactaagaactattcatggc aaaaaatatatattgaaatgaaatttgcaatgtttgtgtttaaaaatctcatccagtgct agcatggtggcacacgtctttaatcccagtacttgggaggcagagatctctatacattca aagcaaccctggtctatatatcaagtttcaggacagccagagctatacacagagagagcc tgtctcaaataaacatacaaacaaaagaacgctccccagactatacaatagatttctata aattaataagaaaaagacccccctttgggagggggcaagcatagtagagtatgcctttaa tcccagcacttgggaagcagaggcaggtagactggatctctatgggttcaaggtcagcct ggtctacataatgaattctaggacaaccagagcttcttagtaagactctgactcaaaaaa gaagaagaaagaagaagaaggagaagaagaagaaagaagaagaagaagaagaagaagaag aagaagaagaagaagaagaagaagaagaagaagaagaaagaggaggaggaggaggaagaa taaaagaaaggaaaaaaaagactcactttttaaaaatcaaaattaaatggcactttataa aagagggcttttatatgcttatccaagggctgccaagcatataaaaaggtgttcaacatc attaaccagccagaaaacacaaagcaggcaaaaagccataccactacacagctatcaccg tgagtgaaacctaagccaataacaacattggtatcaccaaggatgtggctcaccaaagct ctcagatgtcaccagtggaactgggaaatgtacacacgttagaaaactgcttgactgtgc cttctactgacacttgtaaatgctcaccagcaaatgccaacattaacaaagagactgagg gctggggagacggctcattggtaagatgcttgctatacaagcaggaggtcatggatagaa tcaacagacacacagacacacacagacacacagacacacacacacacacacacacacaca cacacacgaggggagccaatcaatgaaatggctcaacaggtaaaggtggaagctgtgtga gcctggcaacctgaggtcaatcttcagaagctatggaaaagcagaaggaagaacacactc cacaaagttgtcccctcatcgccacatgcaggcctgtccacacacattatcatcatcatc ataattaataataatgatgatgatatagtagtagtagtagtagtagtaataacttaaaac tttaaaaaaaagtggtaaatttcccaggttgacagttggccaccacacatgtatctgctc acatgtacccacacacacacacacacacacacacacacacacactcgacataggaataga cactattaagttcttgattgaacatcactttcataggctgacaatacagcccagagggta agggcgcttgctactactccagaaaactcgagtttggtccctgaaataggatagaaagag agaaccagctcctgcaagtaaccctctgctccacatgtgtgctgtgcccacatgcacaca cacatgcacacacacatatgcacacacatgcacgcacacatgcatgtacatacacaaaaa taaagactgcctccatgagagtgtgctatgtgggttaagaaattcctttacacagacgaa gcctatggaccagacagacttaacttgactttcgtgtatacagactaggaaaggatcctt ccagaagccccacgtggataatgagagagcacacccatgttcccatgaaataagagaagg ggtgtggctgaggcagaaggtccagtcatgtcagaacagaggagaaagaatagggccagc ctggtagggtagagttggatggtctagtggacagtctaggaatccggtccaaattctccc tctaccaccagctagccttgtgcccttgggggacaacactcaacctttcccgtctcagct tttctttttgaatagagagaaatggtctgacccatgcataaaagctgcctggtgtggcag gtgctgcttaacataatttttagtccctcgactaaaagggacacaagatgtcccttttag taaaaggggcacagtgagtgctcactgactccacctcagcagacactgcaagagcccaga ataacacaatgggtgccaagtgcctccatgttcaaaagtaagggctaggtattcagtgtg gggtgagcacatcccgccagcacttccgggataacaaagacaggaatgtaaagaagatag tgatgggaaatctttgaaagacttgggaagtgtgtggcagggtccctggacacccaaaga gaagggaaaaggccttcaaaggctcctcagagagctgctgtgtgaccccagaatccgtga gacacaaagattatctggctcatgtctagaccagctggagcaggatctggggctacccca gaaggaagggcactatagctgccccatggaggaatggtttgctaaggaatcctggactaa attatattacttatgacccctgggggtagcgtaagcctagggaggctacaagcagtaagg gagaggcagctatagagggcacagcagctaggtacgtagaaagaagctgtaccccaggga acgcccgtgcaccttgagtcagtgtgtttcctgtgccaggaatgaccaacctatagtagt gtgtgccatgttcctcgtgagcacaggttatgctgcttcctgggcagcactgggcctcct ctcagtccaagtaacaccttccactaccaggaaggttttaccaagagctggaagtcaatg tggggattggagacttctctgaaaaacgttgctcggcttccagactctgccctagcccca ctacagtctactgaacactcctgtttggaactccagcctgacctgcggaagcaactgctc tgtgaagtccagggatgagcagaggttgggagattcttctcttggtttagctttgaataa gagaagggagttgctgctattggcatcttctatagagcaggccctggtgcctagctagtg ttttgtgtgaaccgaccaatattcccaagaacaatcacactgggtggatatttgtcattt ccagtttacacgggagaagaaagacgtccaaaaagataagaatgtagccccacagcccca gagtgtccttgaactctctatgtagccaagacagactttgaactcctggtcctcctgtct ccatctctcacgtgctggggttacaagtgtgcattgccatgctcagtttatatggtgctg gggattgaactcagggctttgtgtctgctaagcaagcaccctagaagccgagctgcagcc cccaccccaccccaccccaccccacccccagagatggtgtcctcttatagcaccatttct gactggtggcatacactgctgttgagtgacggggccaggcccatgtgccttatttctacc ccttgcaagccacgtgcacctaaaggggctccttctctgaccttgggcttcttaCCTGCA AGAAAAATGGCCCCPrimer
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